Viewpoints

• The Harms of Screening: New Attention to an Old Concern
• Nocebo Effects, Patient-Clinician Communication, and Therapeutic Outcomes
• Integrating Technology Into Health Care: What Will It Take?

Original Contribution

Immunogenicity and Tolerability of Recombinant Serogroup B Meningococcal Vaccine Administered With or Without Routine Infant Vaccinations According to Different Immunization Schedules: A Randomized Controlled Trial

Gossger and colleagues assessed the effectiveness of a multicomponent Serogroup B Neisseria meningitidis (MenB) vaccine (4CMenB) in a randomized trial that enrolled 1885 infants. In an editorial, Cohn and Messonnier discuss progress toward an infant MenB vaccine.

• » Abstract
• » Free Full Text
  
• » Editorial: Inching Toward a Serogroup B Meningococcal Vaccine for Infants

Original Contribution

Cefpodoxime vs Ciprofloxacin for Short-Course Treatment of Acute Uncomplicated Cystitis: A Randomized Trial

In a clinical trial that enrolled 300 women with acute uncomplicated cystitis, Hooten and colleagues assessed 30-day clinical cure rates among women randomly assigned to a 3-day regimen of cefpodoxime or a 3-day regimen of ciprofloxacin.

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Original Contribution

Association Between Age at Diagnosis and Disease-Specific Mortality Among Postmenopausal Women With Hormone Receptor–Positive Breast Cancer

In an analysis of data from 9766 postmenopausal women with hormone receptor–positive breast cancer, van de Water and colleagues examined the association between age at diagnosis and breast cancer outcomes.

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Original Contribution

Risk of Intussusception Following Administration of a Pentavalent Rotavirus Vaccine in US Infants

To determine whether recent postlicensure data indicated risk of intussusception from pentavalent rotavirus vaccine (RV5), Shui and colleagues analyzed follow-up data from US infants who collectively received 786 725 doses of RV5.

• » Abstract
• » Full Text
• » Author Video/Audio Interview
• » JAMA Report Video

Clinician's Corner | The Rational Clincal Examination

Does This Patient Have an Infection of a Chronic Wound?

An elderly nursing home resident has a painful pressure ulcer. Reddy and colleagues analyzed 15 studies that assessed clinical signs and symptoms and noninvasive wound cultures to diagnosis wound infections.

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• » CME Course

Editorials

• Inching Toward a Serogroup B Meningococcal Vaccine for Infants
• Medical Education Theme Issue 2012: Call for Papers
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A Piece of My Mind

What Would Patsy Mink Think?

"When I was a third-year medical student, my surgery clerkship director told me on my first day, 'It won't affect your grade, but I want you to know that I don't think women should be doctors.'"

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Clinical Challenge

Rash in an Immunocompromised Patient

A 48-year-old man with low-risk acute promyelocytic leukemia undergoes induction chemotherapy. His clinical course is complicated by low-grade fever and a rash on day 15. What would you do next?

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Readers Respond

A Senior Primary Care Physician Trying to Take Good Care of His Patients

Dr A, a physician of 30 years, moved to a large practice. How would you address his frustration about quality improvement that focuses on populations instead of individual patients?

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Patient Page

Intussusception

For your patients: Information about intussusception. Past JAMA Patient Pages are also freely available in English and Spanish.

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