This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

A Search for Causative Factors

Robert O. Fisch, MD; Eldon B. Berglund, MD; Allyn G. Bridge, MD; Paul R. Finley, MD; Paul G. Quie, MD; Richard Raile, MD

JAMA. 1963;185(10):760-763.

Abstract
Eighteen cases of methemoglobinemia occurred among premature and newborn infants in a hospital nursery. Investigation revealed many suspicious anilinecontaining materials, of which trichlorocarbanilide (TCC) seemed the most likely source of toxicity. The outbreak ceased when hospital procedures were modified extensively. Subsequent laboratory tests, made in an effort to determine the specific offending substance, revealed the importance of careful clinical epidemilogical study in dealing with such situations.

Author Affiliations
Minneapolis

Associate Professor of Pediatrics (Dr. Raile), assistant professors of pediatrics (Drs. Fisch and Quie), Clinical Assistant Professor (Dr. Berglund), Instructor (Dr. Finley), University of Minnesota; Director of Clinical Laboratories, Fairview Hospital (Dr. Finley); Director of Maternal and Child Health, Minnesota Department of Health (Dr. Bridge).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Contribution of Diaper Service Accreditation to Infant Health Care
Livesey
CLIN PEDIATR 1972;11:541-544.
ABSTRACT  

Suspected Adverse Effects of Drugs: Need for Adequate Investigation
Kautz et al.
JAMA 1964;189:269-272.
ABSTRACT