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Max Charles Igloe, MD

JAMA. 1964;189(3):188-190.

Abstract
Methyldopa demonstrated antihypertensive activity when prescribed in initial amounts of 1 gm daily in four divided doses to 51 patients with mild to moderate hypertension. The mean arterial pressure was reduced by an average of 34/18 mm Hg in the supine position and 34/24 mm Hg in the standing position. While methyldopa did not alter the hemogram, urinalysis, or liver-function pattern, febrile reactions and occipital headaches were outstanding side reactions. Other side effects included drowsiness and dry mouth, which were frequent but transient and tolerable.

Author Affiliations
Los Angeles

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

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ANN INTERN MED 1966;65:657-671.
ABSTRACT