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Computer Review of the Literature

Charles D. Wood, PhD; Robert E. Kennedy, MSC; Ashton Graybiel, MC; Richard Trumbull, MSC; Robert J. Wherry, MSC

JAMA. 1966;198(11):1155-1158.

Abstract
A computer library of the literature on anti-motionsickness drugs has been established at the Navy Institute of Aerospace Medicine at Pensacola, Fla. The overall effectiveness of the antihistamines was 70.6%; for the belladonnas it was 50.1%, and for the phenothiazines, 44.9%. The overall results of British studies indicated a greater effectiveness for the belladonnas than for the antihistamines, which is the reverse of the results of US studies. In a recent series of studies dextroamphetamine was found to be a highly effective anti-motion-sickness drug with an overall effectiveness of 64%. The drugs were found to be more effective for motion sickness during flight than for motion sickness at sea.

Author Affiliations
USN; USN; USN; USN

From the Naval Aerospace Medical Institute, Pensacola, Fla. Dr. Wood is with the Department of Pharmacology, University of Arkansas Medical School, Little Rock.

Footnotes
The opinions presented in this communication are not necessarily those of the Department of the Navy.

Reprint requests to Naval Aerospace Medical Institute, Pensacola, Fla 32512 (Dr. Wood).

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