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Philip A. Brunell, MD

JAMA. 1967;199(5):315-317.

Abstract
Ten pregnant women with varicella and one pregnant woman with herpes zoster were studied. Only one of these women had a complicated course characterized by nephritis and hepatitis and the birth of a stillborn infant. One other woman who had vaginal bleeding for a month prior to the onset of varicella aborted two weeks after recovery from varicella. Seven women who were observed to term delivered normal, full-term infants. Large doses of -globulin which were given to four infants whose mothers had varicella within a week prior to delivery failed to produce a detectable rise in serum varicella-zoster (V-Z) antibodies. Three of these infants who were born without V-Z serum antibody got neonatal varicella. All recovered uneventfully.

Author Affiliations
From the Department of Pediatrics, New York University School of Medicine, New York.

Footnotes
Reprint requests to 550 First Ave, New York 10016 (Dr. Brunell).

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