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Their Significance as a Public Health Problem

Virginia Apgar, MD; Gabriel Stickle, MA

JAMA. 1968;204(5):371-374.

Abstract
Abnormal conditions of congenital origin are a leading cause of death and disability in the United States. An estimated 500,000 fetal deaths and at least 62,000 deaths among the live-born are associated with birth defects each year. An estimated 15 million persons have one or more congenital defects which affect their daily lives. Birth defects constitute a leading cause of hospitalization of children.

Author Affiliations
From the Division of Congenital Malformations, Research Department, the National Foundation, New York.

Footnotes
Read before the Section on Obstetrics and Gynecology at the 116th annual convention of the American Medical Association, Atlantic City, NJ, June 21, 1967.

Reprint requests to 800 Second Ave, New York 10017 (Dr. Apgar).

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