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Lionel Grossbard, MD; David Rosen, MD; Eve McGilvray, MD; Adriana de Capoa, MD; Orlando Miller, MD; Arthur Bank, MD

JAMA. 1968;205(11):791-793.

Abstract
Acute leukemia occurred in a user of several hallucinogenic drugs (lysergic acid diethylamide [LSD], mescaline, marihuana, and amphetamines). The leukemic leukocytes of the patient contained a Ph¹-like chromosome; lymphocytes transformed with phytohemagglutinin did not show chromosome breaks. A Ph¹-like chromosome has only rarely been reported in either acute leukemia or in cultured lymphocytes of individuals ingesting LSD.

Author Affiliations
From the departments of medicine (Drs. Grossbard, Rosen, and Bank), obstetrics and gynecology (Drs. de Capoa and Miller), and pediatrics (Dr. McGilvray), Columbia University College of Physicians and Surgeons and the Presbyterian Hospital, New York.

Footnotes
Reprint requests to 630 W 168th St, New York 10032 (Dr. Grossbard).

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