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Limitations of Lactated Ringer's Solution in Massive Fluid Replacement
Phillip O. Bridenbaugh, MD;
Robert I. Balfour, MD;
Daniel C. Moore, MD;
L. Donald Bridenbaugh, MD
JAMA. 1968;206(10):2313-2315.
Abstract
Extracellular fluid volume was maintained by administration of 14 liters whole blood, 28 liters lactated Ringer's solution, and 2 liters of dextran 70 in a patient suffering severe hemorrhage (25 liters) during a 4 1/2-hour decompressive cervical laminectomy. Lactated Ringer's solution proved advantageous as a supplement to the whole blood because of its ready availability, modest cost and freedom from hepatitis virus. However, determinations of the hematocrit value and total serum protein level demonstrated the limitation of lactated Ringer's solution in supplying colloid for total volume replacement.
Author Affiliations
From the Department of Anesthesiology, The Mason Clinic, Seattle.
Footnotes
Reprint requests to 1118 Ninth Ave, Seattle 98101 (Dr. P. Bridenbaugh).
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