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Depression of Poison Ivy Skin Tests by Measles Vaccine
MAJ Ralph Blumhardt, MC;
CPT Joseph E. Pappano, Jr., MC;
LTC Donald G. Moyer, MC
JAMA. 1968;206(12):2739-2741.
Abstract
The degree of sensitivity to varying dilutions of a poison ivy antigen was established by patch tests in seven individuals. Administration of the live, attenuated measles virus vaccine (Schwarz) to this small group of subjects resulted in a temporary reduction of sensitivity, most marked (33% of control values) between the third and sixth weeks postimmunization. At nine weeks, the sensitivity was returning to preimmunization levels. Five control subjects showed no change in their degree of sensitivity.
Author Affiliations
USA; USA; USA
From the Department of Medicine (Dr. Blumhardt), Allergy Service (Dr. Pappano), and Dermatology Service (Dr. Moyer), Madigan General Hospital, Tacoma, Wash. Dr. Blumhardt is now at the US Army Hospital, Ft Carson, Colo.
Footnotes
This material has been reviewed by the Office of the Surgeon General, Department of the Army, and there is no objection to its presentation and/or publication. This review does not imply an indorsement of the opinions advanced or any recommendation of such products as may be named.
Reprint requests to PO Box 99, Madigan General Hospital, Tacoma, Wash 98431.
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