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Timothy M. Harris, MD; Marilyn Gray; Thomas L. Petty, MD; Robert Mueller, MD

JAMA. 1968;206(13):2885-2887.

Abstract
Ventilators which provide a 40% mixture of oxygen with air are commonly employed in the management of respiratory failure. When set on air mix and powered by compressed-oxygen sources, the ventilators may deliver high and unpredictable partial pressures of oxygen. Measurement of inspired partial pressures of oxygen (PIO₂) is important in identifying patients receiving excessive oxygen concentrations, and in monitoring patients in respiratory failure. The technique for sampling and measuring the PIO₂ is exceedingly simple and reliable. The difference between the partial pressure of oxygen in the inspired gas and the partial pressure of oxygen in the arterial blood is an approximate indicator of the effective oxygen transport in the lungs.

Author Affiliations
From the Respiratory Care Unit, Department of Medicine, University of Colorado Medical Center, Denver. Dr. Harris is now at the Albany (NY) Medical College.

Footnotes
Reprint requests to Department of Medicine, Division of Pulmonary Disease. Albany Medical College, Albany, NY 12208 (Dr. Harris).

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