This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

David D. Porter, MD; Ira Wimberly; Matilda Benyesh-Melnick, MD

JAMA. 1969;208(9):1675-1679.

Abstract
Serum samples from 224 children of low socioeconomic status and from 281 children and 120 young adults of high socioeconomic status were evaluated for immunofluorescent antibodies to EB virus and for complement-fixing antibodies to herpes simplex virus and to cytomegalovirus. Regardless of socioeconomic status, approximately 45% of children 7 to 24 months of age were found to have antibody to EB virus, and by 4 to 7 years of age, the percentage of children with antibody approximated that of 73% to 90% found in the adults. Children of a low socioeconomic status had a slightly higher prevalence of EB antibody, and a markedly higher prevalence of herpes simplex antibody, than those of a high socioeconomic status. This study indicates that infection with EB virus occurs much earlier and more commonly in children than infections with herpes simplex virus and cytomegalovirus do.

Author Affiliations
From the Department of Virology and Epidemiology, Baylor College of Medicine, Houston.

Footnotes
Reprint requests to 1200 Moursund Ave., Houston 77025 (Dr. Benyesh-Melnick).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Robust In Vivo Transduction of a Genetically Stable Epstein-Barr Virus Episome to Hepatocytes in Mice by a Hybrid Viral Vector
Gallaher et al.
J. Virol. 2009;83:3249-3257.
ABSTRACT | FULL TEXT  

Early environmental exposure and the development of lupus
Edwards and Cooper
Lupus 2006;15:814-819.
ABSTRACT  

Human Immunodeficiency Virus Induction of Corticotropin in Lymphoid Cells
Hashemi et al.
J. Clin. Endocrinol. Metab. 1998;83:4373-4381.
ABSTRACT | FULL TEXT  

Neonatal Herpes Simplex Virus Infection in King County, Washington: Increasing Incidence and Epidemiologic Correlates
Sullivan-Bolyai et al.
JAMA 1983;250:3059-3062.
ABSTRACT  

Virus-induced corticosterone in hypophysectomized mice: a possible lymphoid adrenal axis
Smith et al.
Science 1982;218:1311-1312.
ABSTRACT  

Infectious Mononucleosis and the Epstein-Barr Virus
Rapp and Hewetson
Arch Pediatr Adolesc Med 1978;132:78-86.
ABSTRACT  

Herpetic Pneumonia in Alcoholic Hepatitis
Caldwell and Porter
JAMA 1971;217:1703-1703.
ABSTRACT  

Etiologic Study of Nasopharyngeal Cancer
Miller et al.
Arch Otolaryngol Head Neck Surg 1971;94:104-108.
ABSTRACT  

A Seroepidemiologic Study of Infectious Mononucleosis: The Development of EB Virus Antibody in a Military Population
Lehane
JAMA 1970;212:2240-2242.
ABSTRACT  

Cornea and Sclera
Laibson
Arch Ophthalmol 1970;83:637-657.
 

Association of Stomatitis and Paronychias Due to Herpes Simplex
Muller and Herrmann
Arch Dermatol 1970;101:396-402.
ABSTRACT  

Herpesviruses and Cancer
Goodheart
JAMA 1970;211:91-96.
ABSTRACT