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Effects of Burns on the HeartA Clinicopathological Study in Children
Vijay V. Joshi, MD
JAMA. 1970;211(13):2130-2134.
Abstract
Analysis of clinicopathological data of seven fatal cases of burned children showed that congestive heart-failure was a major factor in their deaths. The possibility of an overload of fluid administered intravenously was ruled out. No detailed account of cases of this type was found in the literature. The patients had infected burns, prolonged clinical course, anemia, episodes of hypokalemia and hyperkalemia, systemic hypertension, and hypoproteinemia. At autopsy, all cases showed cardiomegaly with focal inflammatory and degenerative lesions of the myocardium. There is a possible relationship of the above factors and myocardial lesions to congestive heart-failure. Physicians should be alert to the possibility of congestive heart-failure in burned children.
Author Affiliations
From the Department of Pathology, Medical College of Virginia, Richmond. Dr. Joshi is now with the University of Western Ontario, Canada.
Footnotes
Reprint requests to the Department of Pathology, University of Western Ontario, London, Ontario, Canada (Dr. Joshi).
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