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Richard K. Winkelmann, MD

JAMA. 1970;211(3):472-475.

Abstract
Three cases of systemic lupus erythematosus and panniculitis illustrate the inflammatory, sclerotic, and ulcerative clinical features of the skin lesions. Histopathologic diagnosis is characterized by poikiloderma, lymphocytic inflammation, hyaline necrosis of collagen and fat, and focal calcification. The lesions respond to antimalarial and corticosteroid therapy, and full-thickness skin grafts are well tolerated. The differential diagnosis includes other forms of panniculitis and localized scleroderma.

Author Affiliations
From the Section of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Read before the American Dermatological Association, Scottsdale, Ariz, April 22, 1969.

Reprint requests to Mayo Clinic, Rochester, Minn 55901.

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