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Ischemic Electrocardiographic Changes After Truncal Vagotomy
Gregory J. Gallivan, MD;
Howard Levine, MD;
Andrew J. Canzonetti, MD
JAMA. 1970;211(5):798-801.
Abstract
Preoperative and postoperative evaluation (including clinical cardiac status, electrocardiograms, and serum enzyme levels) of 106 patients undergoing transabdominal truncal vagotomy during a 17-month period produced evidence of ischemic ECG abnormalities. Although ischemic ECG changes have been reported in patients with subarachnoid hemorrhage, as well as in those with metabolic and gastrointestinal disorders, such findings, to our knowledge, have not been previously documented in vagotomized humans. A 9% occurrence of moderate to marked ischemia with prolonged QT interval exceeds fourfold the highest reported incidence of postoperative myocardial infarction. The ECG abnormalities were noted primarily one day after vagotomy, lasted one to several weeks, and were not accompanied by correlative clinical or serum enzyme level changes. All patients undergoing vagotomy should have ECGs performed preoperatively and postoperatively.
Author Affiliations
From the departments of surgery (Drs. Gallivan and Canzonetti) and medicine (Dr. Levine), New Britain (Conn) General Hospital, and the Department of Medicine, University of Connecticut Health Center, School of Medicine, Hartford (Dr. Levine). Dr. Gallivan is now with the University of Texas Southwestern Medical School, Dallas.
Footnotes
Read in part before the Connecticut Society of American Board Surgeons, Wallingford, Conn, Dec 4, 1968, and at the annual meeting of the New England States Chapter, American College of Chest Physicians, Boston, March 29, 1969.
Reprint requests to 736 Stevens Hills Lane, Dallas 75208 (Dr. Gallivan).
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