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  Vol. 211 No. 5, February 2, 1970 TABLE OF CONTENTS
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Hypokalemic Rhabdomyolysis and Myoglobinuria Following Amphotericin B Therapy

LCDR David J. Drutz, MC; J. H. Fan, MD; T. Y. Tai, MD; J. T. Cheng, MD; W. C. Hsieh, MD

JAMA. 1970;211(5):824-826.


Abstract

Amphotericin B-induced hypokalemia progressed to profound muscle weakness, rhabdomyolysis, and myoglobinuria in a patient with cryptococcal meningitis. Incomplete renal tubular acidosis which was present during therapy may have predisposed the patient to renal potassium wasting.



Author Affiliations

USNR

From the Department of Clinical Investigation, US Naval Medical Research Unit 2, Taipei, Taiwan (LCDR Drutz), and the Department of Internal Medicine, National Taiwan University College of Medicine, Taipei (Drs. Fan, Tai, Cheng, and Hsieh). Dr. Drutz is now with the USPHS Hospital and the Cancer Research Institute, University of California Medical Center, San Francisco.


Footnotes

The opinions and assertions contained herein are those of the authors and are not to be construed as official, or reflecting the views of the Navy Department or the naval service at large.

Reprint requests to Publications Editor, US Naval Research Unit 2, APO San Francisco 96263.



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

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Arch Intern Med 1973;132:891-894.
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Rhabdomyolysis and Myoglobinuria: Association With Hypokalemia of Renal Tubular Acidosis
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JAMA 1972;220:967-969.
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Renal Tubular Acidosis Due to Amphotericin B Nephrotoxicity
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Arch Intern Med 1971;127:241-244.
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