This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

David P. Stevens, MD; Lewellys F. Barker, MD; Alfred S. Ketcham, MD; Harry M. Meyer, Jr., MD

JAMA. 1970;211(8):1341-1344.

Abstract
Forty-one patients who underwent whole blood transfusion during aggressive surgical excision of solid tumors were followed up prospectively for evidence of active cytomegalovirus (CMV) infection. Fourfold or greater elevation in complement-fixing antibody titers developed in 13 (32%) of the patients within 8 to 16 weeks after surgery. Cytomegalovirus was isolated from one of these patients. The incidence of antibody rise correlated best with volume of blood received, but it did not appear to be related to either the time of storage of transfused blood or the type of operative procedure performed. No clinical illness could be attributed to CMV infection in these patients.

Author Affiliations
From the Laboratory of Viral Immunology, Division of Biologics Standards (Drs. Stevens, Barker, and Meyer), and Surgery Branch, National Cancer Institute (Dr. Ketcham), National Institutes of Health, Bethesda, Md. Dr. Stevens is now with University Hospitals, Cleveland.

Footnotes
Reprint requests to Room 2B-12, Bldg 29A, National Institutes of Health, Bethesda, Md 20014 (Dr. Barker).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies
Nassetta et al.
J Antimicrob Chemother 2009;63:862-867.
ABSTRACT | FULL TEXT  

Detection of human cytomegalovirus in peripheral blood lymphocytes in a natural infection
Schrier et al.
Science 1985;230:1048-1051.
ABSTRACT  

A New Cytomegalovirus Syndrome?
HANSHAW
Arch Pediatr Adolesc Med 1979;133:475-476.
ABSTRACT  

Enhancement of mouse cytomegalovirus infection during host-versus-graft reaction
Wu et al.
Science 1975;190:56-58.
ABSTRACT  

Spontaneous Cytomegalovirus Mononucleosis: Clinical and Laboratory Observations in Nine Cases
JORDAN et al.
ANN INTERN MED 1973;79:153-160.
ABSTRACT  

Gastrointestinal Cytomegalovirus Infection
Rosen et al.
Arch Intern Med 1973;132:274-276.
ABSTRACT  

Cytomegalovirus Infection In Patients Receiving Long-Term Hemodialysis
Nakao et al.
JAMA 1971;217:697-698.
ABSTRACT  

Disseminated Cytomegalic Inclusion Disease in a Burned Adult
Nash et al.
JAMA 1970;214:587-589.
ABSTRACT  

Latent Cytomegalovirus Infection and Blood Transfusion
KANTOR and JOHNSON
ANN INTERN MED 1970;73:333-334.
ABSTRACT