This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Matthew E. Levison, MD; Donald Kaye, MD; Gerald L. Mandell, MD; Edward W. Hook, MD

JAMA. 1970;211(8):1355-1357.

Abstract
The records of 268 patients with bacteriologically confirmed endocarditis who were hospitalized between 1944 and 1967 showed 251 with one episode each and 17 with more than one episode. Of the latter group 14 had two episodes and 3 patients had three episodes each. These patients differed from those with single episodes in the following respects: -hemolytic streptococcal endocarditis was significantly more frequent, congenital heart disease was significantly more common, and patients with multiple episodes were younger at the time of initial infection. A cure was achieved in 33 of the 37 multiple episodes (89%), which compares favorably with results in patients with single episodes. Relapse occurred in the other four episodes, but cure was achieved on retreatment.

Author Affiliations
From the Department of Medicine, New York Hospital—Cornell Medical Center, New York. Dr. Kaye is now with Woman's Medical College of Pennsylvania, Philadelphia. Drs. Mandell and Hook are now with the University of Virginia School of Medicine, Charlottesville.

Footnotes
Reprint requests to 3300 Henry Ave, Philadelphia 19129 (Dr. Kaye).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Prevention of infective endocarditis: Guidelines from the American Heart Association: A guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group
Wilson et al.
Journal of the American Dental Association 2008;139:3S-24S.
ABSTRACT | FULL TEXT  

Prevention of Infective Endocarditis: Guidelines From the American Heart Association: A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group
Wilson et al.
Circulation 2007;116:1736-1754.
ABSTRACT | FULL TEXT  

Prevention of infective endocarditis: Guidelines from the American Heart Association: A guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group
Wilson et al.
Journal of the American Dental Association 2007;138:739-760.
ABSTRACT | FULL TEXT  

Should HIV Endocarditis Patients Be Operated On? A Case Presentation
Yee
VASC ENDOVASCULAR SURG 1991;25:417-420.
ABSTRACT  

Infective Endocarditis: An Analysis Based on Strict Case Definitions
VON REYN et al.
ANN INTERN MED 1981;94:505-518.
ABSTRACT  

Changing Patterns of Susceptibility of Common Bacterial Pathogens to Antimicrobial Agents
FINLAND
ANN INTERN MED 1972;76:1009-1036.
ABSTRACT