This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Report of a Case in a Young Adult Treated With Gentamicin

Martin C. McHenry, MD; Donald F. Dohn, MD; Fred R. Tingwald, MD; Thomas L. Gavan, MD

JAMA. 1970;212(1):156-158.

Abstract
Refractory meningitis due to Escherichia coli occurred in a young adult with a fracture of the temporal bone. Intramuscular administration of gentamicin resulted in detectable concentrations of this drug in the cerebrospinal fluid (CSF), and temporary control of infection. For permanent bacteriologic cure, intramuscular and intrathecal therapy with gentamicin was ultimately required. The subcutaneous CSF reservoir of Ommaya provided a safe, convenient way to administer intrathecal therapy and to monitor its progress.

Author Affiliations
From the Department of Internal Medicine, Section of Infectious Disease (Dr. McHenry); the Department of Neurologic Surgery (Dr. Dohn); the Department of Otolaryngology (Dr. Tingwald); and the Department of Clinical Pathology (Dr. Gavan), Cleveland Clinic Foundation.

Footnotes
Reprint requests to 2020 E 93rd St, Cleveland 44106 (Dr. McHenry).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Intrathecal Amikacin Administration: Use in the Treatment of Gentamicin-Resistant Klebsiella pneumoniae Meningitis
Hamory et al.
JAMA 1976;236:1973-1974.
ABSTRACT  

Gram-Negative Bacillary Meningitis Therapy: Polyradiculitis Following Intralumbar Aminoglycoside Administration
Hollifield et al.
JAMA 1976;236:1264-1266.
ABSTRACT  

Group D Enterococcal Meningitis: Clinical and Therapeutic Considerations With Report of Three Cases and Review of the Literature
Bayer et al.
Arch Intern Med 1976;136:883-886.
ABSTRACT  

Intracisternal and Intrathecal Injections of Gentamicin in Enterobacter Meningitis
Saad and Farrar
Arch Intern Med 1974;134:738-740.
ABSTRACT  

Intrathecal Gentamicin
SMILACK and MCCLOSKEY
ANN INTERN MED 1972;77:1002-1003.
ABSTRACT  

Meningitis due to Escherichia Coli 0126 :B16: Report of a Fatal Case in a Girl Aged 14
Zoumboulakis et al.
CLIN PEDIATR 1972;11:603-604.
 

Treatment of Gram-Negative Bacillary Meningitis in Adults
RAHAL
ANN INTERN MED 1972;77:295-302.
ABSTRACT  

Gentamicin Dosages for Renal Insufficiency: Adjustments Based on Endogenous Creatinine Clearance and Serum Creatinine Concentration
MCHENRY et al.
ANN INTERN MED 1971;74:192-197.
ABSTRACT