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Nial R. Morgan, MD; Theodore R. Waugh, MD; Michael D. Boback, MD

JAMA. 1970;212(3):476-478.

Abstract
A clinical syndrome follows accidental self-administration of secobarbital intra-arterially. It is characterized by immediate, severe, burning pain radiating into the hand. Tense muscle edema and necrosis developed during 24 to 48 hours in the presence of an intact radial pulse. Confusion with cellulitis may delay accurate diagnosis. Early fasciotomy can prevent the development of Volkmann's ischemic contracture.

Footnotes
Reprint requests to the Division of Orthopedic Surgery, University of California, Irvine 92664 (Dr. Waugh).

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