This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Freddy Homburger, MD; Eörs Bajusz, MD, PhD

JAMA. 1970;212(4):604-610.

Abstract
The resemblance of five new constitutional (hereditary) diseases in inbred Syrian hamsters (muscular dystrophy, cardiomyopathy with congestive heart failure, obesity, adrenal adenomatosis, and progressive hind-leg paralysis) to human disease entities makes these animals useful for systematic experimental study. The hamsters have also demonstrated peculiar inherited susceptibilities to teratogenic agents (thalidomide), poisoning by cyclamates through coronary and systemic calcinosis, and the carcinogenic activity of polycyclic hydrocarbons.

Author Affiliations
From the Bio-Research Institute, Cambridge, Mass.

Footnotes
Reprint requests to 9 Commercial Ave, Cambridge, Mass 02141 (Dr. Homburger).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Molecular Pathogenesis of Muscle Degeneration in the {delta}-Sarcoglycan-Deficient Hamster
Straub et al.
Am. J. Pathol. 1998;153:1623-1630.
ABSTRACT | FULL TEXT  

Calcium antagonist receptors in cardiomyopathic hamster: selective increases in heart, muscle, brain
Wagner et al.
Science 1986;232:515-518.
ABSTRACT  

The Hamster and Pharmacological and Toxicological Research
Laird
Toxicol Pathol 1973;1:24-26.