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David J. Gocke, MD; Harry B. Greenberg; Neil B. Kavey, MD

JAMA. 1970;212(5):877-879.

Abstract
Transfusion of blood containing Australia antigen was associated with development of hepatitis or an antibody response in 74% (31 of 42) recipients. However, hepatitis also occurs in recipients of antigen-negative donor blood. Further study is required to determine precisely how much hepatitis could be prevented by screening donor blood for Australia antigen. At present, it appears that about 25% of transfusion hepatitis could be prevented in this way, and we are optimistic that this figure can be revised upward.

Author Affiliations
From the Department of Medicine, College of Physicians and Surgeons of Columbia University, New York.

Footnotes
Reprint requests to 630 W 168th St, New York 10032 (Dr. Gocke).

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