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Alfred Feingold, MD; James O. Elam, MD; Glen D. Dobben, MD

JAMA. 1970;212(5):879-880.

Abstract
Severe muscle spasms followed inadvertent subarachnoid administration of diatrizoate meglumine (Renografin), demonstrating the dangers of using this and similar compounds for visualizing a catheter which may lie in, or communicate with, the subarachnoid space. If radiopaque contrast must be used, as is usually necessary even with catheters sold as radiopaque, it would seem prudent to use an oil-base contrast medium rather than a water-soluble agent.

Author Affiliations
From the departments of anesthesiology (Drs. Feingold and Elam) and radiology (Dr. Dobben), University of Chicago, Chicago. Dr. Feingold is now at Northwestern University, Chicago.

Footnotes
Reprint requests to 950 E 59th St, Chicago 60637 (Dr. Elam).

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