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I. Factors Affecting the Results of Treatment in 186 Patients

William F. West, MD; Patrick J. Kelly, MD; William J. Martin, MD

JAMA. 1970;213(11):1837-1842.

Abstract
Certain factors affect the success or failure of surgical treatment of chronic osteomyelitis of the major bones of the extremities and the pelvic and shoulder girdles. This study included 186 patients with 217 surgical procedures. Follow-up periods varied from 4 to 14 years. Two important factors affected success: resistance of Staphylococcus aureus to penicillin G potassium or penicillin G sodium and duration of infection. Either of these factors alone did not mitigate against a successful result but when both were present in an etiologic group, such as chronic osteomyelitis in a fracture with union, failure was more frequent than success. Other factors associated with failure, such as scarred soft tissues and bony sclerosis, are a reflection of prolonged disease.

Author Affiliations
From the Mayo Graduate School of Medicine, University of Minnesota (Dr. West) and the sections of orthopedic surgery (Dr. Kelly) and medicine (Dr. Martin), Mayo Clinic and Mayo Foundation, Rochester, Minn.; Dr. Martin died May 19,1970.

Footnotes
Read before the Section on Orthopedic Surgery at the 118th annual convention of the American Medical Association, New York, July 1, 1969.

Reprint requests to Section of Publications, Mayo Clinic, Rochester, Minn 55901.

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