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MAJ E. Dale Everett, MC; Kermit L. Newcomer, MD; James Anderson, MD; James Bergin, MD; Edwin L. Overholt, MD

JAMA. 1970;213(11):1849-1852.

Abstract
Two patients with Goodpasture's syndrome with severe pulmonary involvement and mild renal disease were treated with mercaptopurine and prednisone for seven to eight months. Each was followed up closely with serial renal function studies and renal biopsies. In both patients, the Addis counts became normal and in patient 1 proteinuria cleared. Follow-up renal biopsies disclosed focal glomerular fibrosis in patient 1 and unchanged mild proliferative glomerulonephritis in the second. There was no further pulmonary involvement.

Author Affiliations
USA

From the Department of Medicine, Fitzsimons General Hospital, Denver.

Footnotes
This material has been reviewed by the office of the Surgeon General, Department of the Army, and there is no objection to its presentation and/or publication. This review does not imply any indorsement of the opinions advanced or any recommendation of such products as may be named.

Reprint requests to Fitzsimons General Hospital, Denver 80240 (MAJ Everett).

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