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  Vol. 213 No. 11, September 14, 1970 TABLE OF CONTENTS
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Esophageal Moniliasis

The Spectrum of the Disease

Douglas J. Sheft, MD; Gary Shrago, MD

JAMA. 1970;213(11):1859-1862.


Abstract

Candida albicans is a saprophytic organism under normal circumstances and a limited pathogen when present in large numbers. With impaired defense mechanisms, however, or long-term antibiotic therapy, it can become a significant pathogen. The clinical symptoms and roentgenographic findings present a spectrum of changes depending on the degree of esophageal involvement. Painful swallowing or substernal chest pain are the most common symptoms. Roentgenographic study reveals changes varying from minor mucosal irregularities and submucosal edema to extensive ulcerations. Roentgenographic examination of the esophagus is a useful method for establishment of the diagnosis.



Author Affiliations

From the Department of Radiology, University of California San Francisco Medical Center.


Footnotes

Reprint requests to University of California, San Francisco Medical Center, Parnassus and Third avenues, San Francisco 94122 (Dr. Sheft).



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