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Relation to Pyelonephritis

Arjan D. Amar, MB, BS, FRCS(C)

JAMA. 1970;213(2):293-294.

Abstract
Calicotubular backflow, previously reported to occur during retrograde or excretory urographic study, was observed during voiding cystography of eight patients with vesicoureteral reflux. The phenomenon is probably more common than has been demonstrated by present methods. Its connection with pyelonephritis in patients with reflux appears not to have been appreciated. Where calicotubular backflow occurs, bacteria entering the renal pelvis as a result of vesicoureteral reflux can invade the renal parenchyma to initiate, complicate, and perpetuate pyelonephritis.

Author Affiliations
From the Department of Urology, the Permanente Medical Group, Kaiser Foundation Hospital, Walnut Creek, Calif; and the Division of Urology, University of California Medical Center, San Francisco.

Footnotes
Reprint requests to 1425 S Main St, Walnut Creek, Calif 94590 (Dr. Amar).

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