You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT JAMA
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 214 No. 2, October 12, 1970 TABLE OF CONTENTS
  JAMA
  •  Online Features
  ARTICLES
 This Article
 •References
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in JAMA
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Thyroid Neoplasia as Late Effect of Exposure to Radioactive Iodine in Fallout

Robert A. Conard, MD; Brown M. Dobyns, MD; Wataru W. Sutow, MD

JAMA. 1970;214(2):316-324.


Abstract

Accidental exposure of people of Rongelap Island to radioactive fallout and particularly to radioactive iodines in the fallout has resulted in the development of thyroid abnormalities in 21 of 67 of these people, 3 with malignant lesions, 16 with benign adenomatous nodules, and 2 with atrophy of the gland with hypothyroidism. The preponderance of lesions occurred in children exposed at less than 10 years of age who had received a greater thyroid exposure. Growth retardation associated with hypothyroid tendency was noted in some children who appear to be responding favorably to thyroid hormone medication. Thyroidectomy, partial to complete, has been carried out on 18 patients. Risk for thyroid cancer from radioactive iodine exposure in this group does not appear to be very different from that reported following x-irradiation.



Author Affiliations

From the Medical Department, Brookhaven National Laboratory, Upton, NY (Dr. Conard); Case Western Reserve University School of Medicine at Cleveland Metropolitan General Hospital, Cleveland (Dr. Dobyns); and the M. D. Anderson Hospital & Tumor Institute, Houston (Dr. Sutow).


Footnotes

Reprint requests to Brookhaven National Laboratory, Upton, NY 11973 (Dr. Conard).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

BRAF mutation in thyroid cancer
Xing
Endocr Relat Cancer 2005;12:245-262.
ABSTRACT | FULL TEXT  

The Changing Incidence and Spectrum of Thyroid Carcinoma in Tasmania (1978-1998) during a Transition from Iodine Sufficiency to Iodine Deficiency
Burgess et al.
J. Clin. Endocrinol. Metab. 2000;85:1513-1517.
ABSTRACT | FULL TEXT  

High Prevalence of RET/PTC Rearrangements in Ukrainian and Belarussian Post-Chernobyl Thyroid Papillary Carcinomas: A Strong Correlation between RET/PTC3 and the Solid-Follicular Variant
Thomas et al.
J. Clin. Endocrinol. Metab. 1999;84:4232-4238.
ABSTRACT | FULL TEXT  

The Management of Graves' Disease in Children, with Special Emphasis on Radioiodine Treatment
Rivkees et al.
J. Clin. Endocrinol. Metab. 1998;83:3767-3776.
FULL TEXT  

Radioiodine for Hyperthyroidism: Where Do We Stand After 50 Years?
Cooper
JAMA 1998;280:375-376.
FULL TEXT  

The Endocrine Effects of Nonhormonal Antineoplastic Therapy
Yeung et al.
Endocr. Rev. 1998;19:144-172.
ABSTRACT | FULL TEXT  

Pediatrics in the Marshall Islands
Dungy et al.
CLIN PEDIATR 1984;23:29-32.
ABSTRACT  

Radiation Dose in the Selection of 131I or Surgical Treatment for Toxic Thyroid Adenoma
GORMAN and ROBERTSON
ANN INTERN MED 1978;89:85-90.
ABSTRACT  

Radiation Exposure and Thyroid Cancer
Greenspan
JAMA 1977;237:2089-2091.
ABSTRACT  

Plasma Thyroglobulin in Detecting Thyroid Carcinoma after Childhood Head and Neck Irradiation
SCHNEIDER et al.
ANN INTERN MED 1977;86:29-34.
ABSTRACT  

Solitary Thyroid Nodules
Liechty et al.
Arch Surg 1977;112:59-61.
ABSTRACT  

Thyroid Nodularity in Children
Rallison et al.
JAMA 1975;233:1069-1072.
ABSTRACT  

Thyroid Carcinoma After Exposure to Atomic Radiation: A Continuing Survey of a Fixed Population, Hiroshima and Nagasaki, 1958-1971
PARKER et al.
ANN INTERN MED 1974;80:600-604.
ABSTRACT  

Thyroid Carcinoma and Radiation: A Chicago Endemic
DeGroot and Paloyan
JAMA 1973;225:487-491.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1970 American Medical Association. All Rights Reserved.