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II. Effect of a Closed Sterile Drainage System

George F. Thornton, MD; Vincent T. Andriole, MD

JAMA. 1970;214(2):339-342.

Abstract
Fifty-one abacteriuric patients requiring prolonged catheter drainage were studied with a new closed sterile drainage system including a nonreturn valve designed to limit reflux of urine from collection bag to drainage tube. Twenty-eight patients remained abacteriuric during the entire period of catheter drainage. In 20 of 27 instances of bag contamination, a delay of at least 24 hours was noted before bladder urine became infected. Closed sterile drainage of the urinary bladder is effective in preventing catheter associated urinary tract infections for short periods. Ascending infection throngh the lumen of the drainage tube is the major pathway by which bacteria infect bladder urine.

Author Affiliations
From the Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn (Drs. Thornton and Andriole); and the West Haven (Conn) Veterans Administration Hospital (Dr. Thornton). Dr. Andriole is an established investigator of the American Heart Association.

Footnotes
Read before the Symposium on Management of Urinary Infection at the 118th annual convention of the American Medical Association, New York, July 17, 1969.

Reprint requests to 333 Cedar St, New Haven, Conn 06511 (Dr. Andriole).

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