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William P. McCann, MD; Eoline I. McGowan, MD; Omer L. Burnett, MD; Paul A. Palmisano, MD

JAMA. 1970;214(4):753-754.

Abstract
Salicylate levels were determined in serum from 240 volunteer blood donors who had denied recent drug exposure. Twenty-seven serum samples had levels ranging from 1.6 to 13.6 mg/100 ml, indicating exposure to salicylate preparations, which presumably were not considered by donors to be drugs. The observed elevated salicylate levels might affect adversely an extremely hypersensitive blood or plasma recipient. Salicylate ingestion might also suppress fever in donors.

Author Affiliations
From the departments of pharmacology and clinical pathology, University of Alabama Medical Center, and Birmingham Regional Red Cross Blood Center (Dr. Gowan), Birmingham, Ala.

Footnotes
Reprint requests to 1919 S Seventh Ave, Birmingham, Ala 35233 (Dr. McCann).

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