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Prevalence and Awareness of Sickle Cell Hemoglobin in a Military PopulationDetermination by a Rapid Screening Method
MAJ Richard A. Binder, MC;
MAJ Stephen R. Jones, MC
JAMA. 1970;214(5):909-911.
Abstract
On a prospective study, 1,000 Negro military recruits were screened with a new rapid differential solubility test for sickle cell hemoglobin. A total of 75 had positive screening tests: 73 had sickle cell trait, 1 had sickle cell-hemoglobin C disease, and 1 had sickle-thalassemia disease. There were no false-positive or false-negatives detected. In only five of the 150 individuals questioned was there any awareness of sickle cell states. This test is rapid and reliable and routine screening of the Negro population accompanied by education and genetic counseling is recommended.
Author Affiliations
USA; USA
From the Hematology Service, Department of Medicine, and the Preventive Medicine Service, Department of Hospital Clinics, William Beaumont General Hospital, El Paso, Tex.
Footnotes
This material has been reviewed by the Office of the Surgeon General, Department of the Army, and there is no objection to its presentation or publication. This review does not imply any endorsement of the opinions advanced or any recommendation of such products as may be named.
Reprint requests to 171 Harrison Ave, Boston 02111 (Dr. Binder).
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