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Diagnosis and Treatment

H. Durell Johnson, MD; Warren W. Johnson, MD

JAMA. 1970;214(6):1067-1073.

Abstract
Pneumocystis carinii pneumonia was diagnosed in 19 children with cancer. The diagnosis was made in 14 children by pulmonary needle aspiration and demonstration of the organism by methenamine silver nitrate stain. Two children had tension pneumothorax and one had postaspiration hemoptysis following needle aspiration, but there was no mortality from the procedure. Seventeen children were treated with pentamidine isethionate; nine recovered. Toxicity to pentamidine consisted of elevated blood urea nitrogen levels and hypoglycemia.

Author Affiliations
From St. Jude Children's Research Hospital and the University of Tennessee Medical Units, Memphis.

Footnotes
Read in part before the Southern Society for Pediatric Research, New Orleans, Nov 25, 1968, and the American Association for Cancer Research, San Francisco, March 24, 1969.

Reprint requests to 332 N Lauderdale, PO Box 318, Memphis 38101 (Dr. H. Johnson).

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