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Melvin H. Freedman, MD; Gerald S. Gilchrist, MB; G. Denman Hammond, MD

JAMA. 1970;214(9):1677-1680.

Abstract
Despite speculation that infectious mononucleosis could be an abortive form of acute lymphatic leukemia, four children under our observation developed both diseases concurrently. Infectious mononucleosis preceded acute leukemia by three months in one case and occurred at various times during hematologic remission in the others. A review of these and five similar cases, reported previously, suggests that infectious mononucleosis is an intercurrent illness which is etiologically unrelated to acute leukemia.

Author Affiliations
From the Division of Hematology, Childrens Hospital of Los Angeles, and the Department of Pediatrics, University of Southern California, Los Angeles.

Footnotes
Reprint requests to 4650 Sunset Blvd, Los Angeles 90027 (Dr. Gilchrist).

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ABSTRACT