This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Steven Arthur Friedman, MD; Stuart E. Hirsch, MD

JAMA. 1971;217(11):1549-1550.

Abstract
Hyperthermia is a known effect of lysergic acid diethylamide (LSD). This is, to our knowledge, the first recorded instance of life-threatening hyperthermia (106.4 F [41.3 C] axillary) in man, following the use of LSD, and may have been dose-related. The hyperthermia was rapidly reversed by alcoholic-ice soaks, hallucinations ended about 18 hours later, and the patient recovered without obvious mental or physical injury.

Author Affiliations
From the Department of Medicine, University of Pennsylvania Division, Philadelphia General Hospital. Dr. Friedman is now with the Department of Pharmacology, University of Pennsylvania School of Medicine. Dr. Hirsch is now with the Department of Ophthalmology, Hospital of the University of Pennsylvania.

Footnotes
Reprint requests to 17 Juniper Rd, Havertown, Pa 19083 (Dr. Friedman).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Drug Fever: A Critical Appraisal of Conventional Concepts: An Analysis of 51 Episodes in Two Dallas Hospitals and 97 Episodes Reported in the English Literature
MACKOWIAK and LeMAISTRE
ANN INTERN MED 1987;106:728-733.
ABSTRACT  

Environmental Heat Illness: An Eclectic Review
Knochel
Arch Intern Med 1974;133:841-864.
ABSTRACT