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A Supplement

William M. Bennett, MD; Irwin Singer, MD; Cecil H. Coggins, MD

JAMA. 1973;223(9):991-997.

Abstract
Four previously published tables describing maintenance dosage intervals for common drugs used in patients with renal disease are supplemented and updated. Emphasis is given to the use of biological half-life and creatinine clearance for modification of the usual dose schedules. Toxic effects and adjustments required by patients undergoing dialysis are also noted.

Author Affiliations
From the Section of Nephrology, Department of Medicine, University of Oregon Medical School, Portland (Dr. Bennett); the Renal-Electrolyte Section, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia (Dr. Singer); and the Renal Unit,; Department of Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston (Dr. Coggins).

Footnotes
Reprint requests to 3181 SW Sam Jackson Park Rd, Portland, Ore 97201 (Dr. Bennett).

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