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Differences in Renal Growth

Sherman J. Silber, MD

JAMA. 1974;228(9):1143-1145.

Abstract
There is an impressive but purely compensatory growth response of the child's kidney transplanted into the uremic adult, but no hypertrophy or hypotrophy of the adult's kidney in the uremic child.

Two separate types of renal growth seem to occur. Compensatory hypertrophic growth is a rapid reversible response to a functional nephron deficit. Obligatory growth occurs as one grows up, and is not reversible.

(JAMA 228:1143-1145, 1974)

Author Affiliations
From the Department of Surgery, Division of Urology, University of Michigan Medical Center, Ann Arbor. Dr. Silber is now with the Department of Surgery, University of Melbourne, Royal Melbourne Hospital, Australia.

Footnotes
Read in part before the 122nd annual convention of the American Medical Association, New York, June 26, 1973.

Reprint requests to Department of Surgery, Division of Urology, University of Michigan Medical Center, Ann Arbor, MI 48104.

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ABSTRACT