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Results of Operative Treatment

John H. Foster, MD; Morton H. Maxwell, MD; Stanley S. Franklin, MD; Kenneth H. Bleifer, MD; Otto H. Trippel, MD; Ormand C. Julian, MD; Paul T. DeCamp, MD; Paul T. Varady, MS

JAMA. 1975;231(10):1043-1048.

Abstract
The blood pressure response to operative treatment in 502 patients with renal artery stenosis and coexisting hypertension was as follows: 51% cured, 15% improved, and 34% failure. The operative mortality was 5.9%. Patients with unilateral fibromuscular disease had a favorable blood pressure response (79.8%) more frequently than the patients with unilateral atherosclerosis (63.4%). In patients with bilateral stenosis, a favorable result occurred in 56%. The anatomic failure rate due to thrombosis of arterial reconstructions, as well as the operative mortality, varied considerably between institutions. If preoperative diagnostic studies demonstrated significant functional disparity between kidneys, and if the operation was anatomically successful, then approximately 80% of these patients were benefited by surgical intervention.

(JAMA 231:1043-1048, 1975)

Author Affiliations
From the Vanderbilt University School of Medicine, Nashville, Tenn (Dr. Foster); the Department of Medicine (Drs. Franklin, Bleifer, and Maxwell), University of California at Los Angeles; Nephrology and Hypertension Service (Mr. Varady), Mt. Sinai Division, Cedars-Sinai Medical Center, Los Angeles (Dr. Maxwell); Northwestern University Medical School, Evanston, III (Dr. Trippel); the University of Illinois Medical School, Chicago (Dr. Julian); and Department of Surgery, Ochsner Foundation Hospital, New Orleans (Dr. DeCamp). Dr. Julian is now Professor Emeritus at the Rush Medical College, Chicago.

Footnotes
This is a report of the Cooperative Study of Renovascular Hypertension.

Reprint requests to Vanderbilt University School of Medicine, 21st St and Garland, Nashville, TN 37232 (Dr. Foster).

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