Hyperosmolar nonketotic syndrome and steroid diabetes. Occurrence after renal transplantation
J. E. Woods, H. Zincke, P. J. Palumbo, W. J. Johnson, C. F. Anderson, P. P. Frohnert and F. J. Service
So-called steroid (glucocorticoids) diabetes developed in 11 (5.5%) of 202
patients receiving 216 renal allografts between December 1963 and June
1974. In three of the 11 patients, hyperosmolar nonketotic syndrome was
present at diagnosis; all of the three recovered. Eight of the 11 patients
survived with functioning allografts, and only one of the eight requires
insulin. Hyperglycemia has been detected in most transplant patients tested
in the immediate postoperative period. Factors (including stress from
surgery and treatment with drugs such as furosemide) predispose to this
condition.
