Monoclonal IgM immunoglobulinemia in psoriatic arthritis
J. E. Lergier and J. D. Gowans
Serum protein electrophoresis in a 61-year-old woman with psoriasis and
psoriatic arthritis showed a monoclonal spike that was identified as
IgM-kappa monoclonal immunoglobulinemia by immunodiffusion and
immunoelectrophoresis. There was no clinical evidence of myeloma,
Waldenstrom macroglobulinemia, or lymphoma, and the M component has not
changed over a three-year observation period. This unusual occurrence may
represent another disease entity that may be associated with nonmyelomatous
monoclonal immunoglobulinemia.
