Pentazocine-induced fibrous myopathy
S. J. Oh, J. L. Rollins and I. Lewis
Fibrous myopathy was found in three patients who had taken pentazocine
intramuscularly for years. Fibrotic induration in the quadriceps and
deltoid muscles, the considerable limitation of motion due to the fibrotic
muscle contracture, and the minimal weakness of involved muscles are the
most characteristic findings in this condition. Results of animal
experiments support the close relationship between myopathy and
pentazocine. This serious complication emphasizes more judicious use of
pentazocine
