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1-Antitrypsin Deficiency, Emphysema, Cirrhosis, and Intestinal Mucosal Atrophy

Alan J. Greenwald, MD; David S. Johnson, MD; Roger M. Oskvig, MD; Carol A. Aschenbrener, MD; Daniel C. Randa, MD

JAMA. 1975;231(3):273-276.

Abstract
An elderly man with long-standing pulmonary emphysema was seen with recent onset of steatorrhea and ascites. He had very low levels of serum ₁-antitrypsin, hepatic cirrhosis, and intestinal mucosal atrophy. We believe that this combination of findings did not occur by chance.

(JAMA 231:273-276, 1975)

Author Affiliations
From the departments of internal medicine (Drs. Greenwald and Randa) and pathology (Drs. Johnson, Aschenbrener, and Oskvig), University of Iowa Hospitals, Iowa City. Dr. Randa is now with the Department of Neurology, University of Minnesota Hospitals, Minneapolis; Dr. Oskvig is now with the Strong Memorial Hospital, Rochester, NY; Dr. Greenwald is now with the Birmingham Medical Group Clinic, Birmingham, Ala.

Footnotes
Reprint requests to Birmingham Medical Group Clinic, 1500 Sixth Ave S, Birmingham, AL 35233 (Dr. Greenwald).

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