Evaluation of an anti-infective combination. Trimethoprim-sulfamethoxazole (Bactrim, Septra)
D. O. Schiffman
Trimethoprim and sulfamethoxazole, combined in a synthetic anti-infective
preparation, act synergistically to inhibit the growth of certain
microorganisms. This combination is effective orally in acute and chronic
urinary tract infections. It also has been used successfully to treat other
infectious conditions, including bacterial upper respiratory tract
infections, ear infections, skin and soft-tissue infections, septicemias,
acute and subacute bacterial endocarditis, enteric fever, brucellosis,
prostatitis, and gonorrhea. It is well tolerated by most patients.