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  Vol. 231 No. 7, February 17, 1975 TABLE OF CONTENTS
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Oral Contraceptives and Stroke in Young Women

Associated Risk Factors

Collaborative Group for the Study of Stroke in Young Women

JAMA. 1975;231(7):718-722.


Abstract

Oral contraceptive use alone, in the absence of smoking, hypertension, or migraine, significantly increases the risk of stroke. Regardless of use or nonuse of these agents, hypertension is a risk factor for development of either thrombotic or hemorrhagic stroke. Regular cigarette smoking and a history of symptoms indicative of migraine also increase the likelihood of one or the other type of stroke, but more information is needed before a definite relationship can be established between these clinical factors and cerebrovascular disease.

(JAMA 231:718-722, 1975)



Author Affiliations

From the Collaborative Group for the Study of Stroke in Young Women, Data Analysis Center, Durham, NC.


Footnotes

For a complete list of participants in this study, see page 722.

Reprint requests to Box 3203, Duke University Medical Center, Durham, NC 27710 (Dr. Heyman).



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