Sickle cell crisis treated by exchange transfusion. Treatment of two patients with heterozygous sickle cell syndrome
M. Green, R. J. Hall, R. G. Huntsman, A. Lawson, T. C. Pearson and P. C. Wheeler
In two patients with severe painful sickle cell crisis and a deteriorating
clinical course, recovery coincided with large-scale exchange transfusions
(6 liters). The one patient, with sickle cell beta thalassemia, achieved a
90% exchange, calculated on the sickle cell hemoglobin present before and
after transfusion. The other patient, with sickle cell hemoglobin Hb A, S,
and (Hb) C disease, also achieved an 80% exchange calculated on the level
of HbA.S. AND C in samples before and after transfusion.