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  Vol. 231 No. 9, March 3, 1975 TABLE OF CONTENTS
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Sickle Cell Crisis Treated by Exchange Transfusion

Treatment of Two Patients With Heterozygous Sickle Cell Syndrome

Malcom Green, MRCP; Roger J. C. Hall, MB, MRCP; Richard G. Huntsman, MD, FRCP, FRCPath; Ann Lawson, MB, BS; Thomas C. Pearson, MB, BS; Patrick C. G. Wheeler, BM, MRCP

JAMA. 1975;231(9):948-950.


Abstract

In two patients with severe painful sickle cell crisis and a deteriorating clinical course, recovery coincided with large-scale exchange transfusions (6 liters).

The one patient, with sickle cell β thalassemia, achieved a 90% exchange, calculated on the sickle cell hemoglobin present before and after transfusion. The other patient, with sickle cell hemoglobin (Hb) C disease, also achieved an 80% exchange calculated on the level of Hb A, S, and C in samples before and after transfusion.

(JAMA 231:948-950, 1975)



Author Affiliations

From the Departments of Medicine (Drs. Green, Hall, Lawson, and Wheeler) and the Department of Haematology (Drs. Huntsman and Pearson), St. Thomas Hospital, London. Dr. Huntsman is now at Lambeth Hospital, London.


Footnotes

Reprints not available.



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