Pulmonary emphysema and liver disease. Occurrence in an alpha-antitrypsin-deficient adult

C. J. Donlan Jr, D. G. Ross, M. Golembieski and J. V. Scutero

An elderly woman manifested both pulmonary and hepatic disease secondary to alpha 1-antitrypsin deficiency. The liver biopsy specimen showed the characteristic findings of this condition, most importantly, the presence of PAS-positive, diastase-resistant intracytoplasmic inclusions.