Subsequent neoplasia in chronic lymphocytic leukemia
D. Manusow and B. H. Weinerman
We performed a retrospective analysis of all 102 cases of chronic
lymphocytic leukemia (CLL) treated by the Hematology Service of the
University of Manitoba from Jan 1, 1955, to April 1, 1974. The incidence of
secondary cancer was compared with that in the Cancer Registry population
of Manitoba of the same age and sex distribution. The risk of all cancers
developing in patients with CLL was threefold that for the age- and
sex-matched population, eightfold for skin cancers, and twofold for all
cancers excluding skin cancer.