Hepatitis B and the HB-SAg carrier. An outbreak related to sexual contact
R. A. Wright
Within six months, acute viral hepatitis, type B, developed in three
individuals associated with a nursing home in Denver. This attack rate, 1.4
cases per 100 patients and employees, was apparently higher than the
reported incidence of hepatitis B in Denver during the same period.
Parenteral inoculations could not be implicated as the means of acquiring
hepatitis B. However, two of the hepatitis patients had had sexual contact
within six months before their illness with an employee who was an
insulin-dependent diabetic and a symptomatic carrier of HB-Sg. In addition,
anti-HB-S antibodies were detected in his homosexual roommate. Although the
chronic carrier was a food-handler, a seroepidemiologic survey of the
employee population showed no spread of HB-Sag by means of food or casual
contact. Only 1 (4.6%) of 22 employees tested had anti-HB-S antibodies.
These results suggest that household and, in particular, sexual contact
with a symptomatic HB-SAg carrier may be an effective nonparenteral or
inapparent parenteral mode of transmitting HB-SAg.