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Hepatitis Types B and Non-BEpidemiologic Background
James W. Mosley, MD
JAMA. 1975;233(9):967-969.
Abstract
Two episodes of acute viral hepatitis occurred in each of 34 patients. One episode in each patient was serologically diagnosable as type B hepatitis on the basis of tests for hepatitis B surface antigen or antibody. The other episode was classified as "non-B" on the basis of seronegativity, reinforced by seropositivity in an alternate bout. An epidemiologic background appropriate to "serum" hepatitis, either transfusion (one bout) or illicit self-injection (46 bouts), was associated just as frequently with serologically non-B episodes as with identified type B disease. The diagnosis of type B hepatitis, therefore, should be made only on the basis of serologic tests specific for hepatitis B virus infection. Other cases of sporadic disease in adults must be labeled "viral hepatitis, type unspecifiable."
(JAMA 233:967-969, 1975)
Author Affiliations
From the Department of Medicine, University of Southern California School of Medicine, and the Liver Service, John Wesley County Hospital, Los Angeles.
Footnotes
Reprint requests to Hepatic Epidemiology Laboratory, John Wesley County Hospital, 2826 S Hope St, Los Angeles, CA 90007 (Dr. Mosley).
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