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Computer Analysis of a Computerized Brain Scan

Richard D. Penn, MD; Randall Walser; Laurens Ackerman, MD, PhD

JAMA. 1975;234(11):1154-1155.

Abstract
Cerebral blood volume in man can be measured by subtracting computerized axial tomogram density measurements taken before from those taken after an intravascular marker is infused into the blood. The average blood volume is 3.0 ml/100 ml of brain tissue, with a range of 2.4 to 4.25. This method can be applied in studying cerebral pathologic conditions. Areas of cerebral edema, surrounding a tumor, have a decreased blood volume.

(JAMA 234:1154-1155, 1975)

Author Affiliations
From the departments of neurosurgery and radiology, Rush-Presbyterian-St Luke's Medical Center, Chicago.

Footnotes
Reprint requests to Rush-Presbyterian-St Luke's Medical Center, 1753 W Congress Parkway, Chicago, IL 60612 (Dr Penn).

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