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  Vol. 234 No. 2, October 13, 1975 TABLE OF CONTENTS
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Cephalexin Monohydrate Suspension

Treatment of Otitis Media

Samuel E. McLinn, MD; James F. Daly, Jr., MD; James E. Jones, MD

JAMA. 1975;234(2):171-173.


Abstract

Cephalexin monohydrate suspension was used in the treatment of 97 children with otitis media. Pretreatment middle-ear exudate specimens in pure or mixed culture yielded Diplococcus pneumoniae in 47 cases, Haemophilus influenzae in 26, Neisseria catarrhalis in 20, group A β-hemolytic streptococci in 13, and Staphylococcus aureus in one. The usual dosage was 100 mg/kg/day given orally in divided doses for 10 to 12 days.

After 48 hours of treatment, follow-up cultures showed that therapy had been successful in 90 children; 81 remained clinically and bacteriologically free of disease for at least three weeks following therapy. Of the seven children for whom therapy failed, H influenzae persisted in five and D pneumoniae in two. Acceptance of the drug was entirely satisfactory with no important side effects encountered.

(JAMA 234:171-173, 1975)



Author Affiliations

From the Harrisburg (Pa) Polyclinic, and the Hersey Medical School, Harrisburg.


Footnotes

Reprint requests to Uptown Professional Bldg, Suite 150, 2645 N Third St, Harrisburg, PA 17110 (Dr. McLinn).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

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