This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Treatment of Otitis Media

Samuel E. McLinn, MD; James F. Daly, Jr., MD; James E. Jones, MD

JAMA. 1975;234(2):171-173.

Abstract
Cephalexin monohydrate suspension was used in the treatment of 97 children with otitis media. Pretreatment middle-ear exudate specimens in pure or mixed culture yielded Diplococcus pneumoniae in 47 cases, Haemophilus influenzae in 26, Neisseria catarrhalis in 20, group A β-hemolytic streptococci in 13, and Staphylococcus aureus in one. The usual dosage was 100 mg/kg/day given orally in divided doses for 10 to 12 days.

After 48 hours of treatment, follow-up cultures showed that therapy had been successful in 90 children; 81 remained clinically and bacteriologically free of disease for at least three weeks following therapy. Of the seven children for whom therapy failed, H influenzae persisted in five and D pneumoniae in two. Acceptance of the drug was entirely satisfactory with no important side effects encountered.

(JAMA 234:171-173, 1975)

Author Affiliations
From the Harrisburg (Pa) Polyclinic, and the Hersey Medical School, Harrisburg.

Footnotes
Reprint requests to Uptown Professional Bldg, Suite 150, 2645 N Third St, Harrisburg, PA 17110 (Dr. McLinn).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Evaluation of Cefaclor in Acute Otitis Media Caused by Ampicillin-resistant H. influenzae
Schwartz et al.
CLIN PEDIATR 1982;21:402-404.
ABSTRACT  

Cephalexin: Clinical and Laboratory Evaluation in Infants and Children
Rudoy and Riley
CLIN PEDIATR 1977;16:639-644.
ABSTRACT