High altitude pulmonary edema. A rare disease?
J. P. Kleiner and W. P. Nelson
Since its original description in the English literature 15 years ago, high
altitude pulmonary edema (HAPE) has been the subject of many reports. The
clinical and hemodynamic features of HAPE are now well recognized, but its
underlying pathophysiology remains unclear. In this article, a case of HAPE
is described and the clinical features, proposed pathogenesis, and
treatment are discussed. (JAMA 234:491-495, 1975).
